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RAR-Related Orphan Receptor A (RORA) (N-Term) Peptid

RORA Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983121

Kurzübersicht für RAR-Related Orphan Receptor A (RORA) (N-Term) Peptid (ABIN983121)

Target

RORA (RAR-Related Orphan Receptor A (RORA))

Spezies

Human

Quelle

  • 16
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-RORA antibody (Catalog #: P100793_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    RORA (RAR-Related Orphan Receptor A (RORA))

    Hintergrund

    RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA

    Protein Interaction Partner: COPS5,EP300,LMO3,MED1,MYOD1,NCOA2,NME1,NME2,NR0B1,PNRC1,PNRC2,PROX1,PSMC5,RORA,SMARCD3,ZXDC,EP300,MYOD1,NME1,PSMC5

    Protein Size: 523

    Molekulargewicht

    59 kDa

    Gen-ID

    6095

    NCBI Accession

    NM_134261, NP_599023

    UniProt

    B6ZGS4
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