Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptid
RIPK3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN983004
Kurzübersicht für Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptid (ABIN983004)
Target
RIPK3
(Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RIPK3 antibody (Catalog #: ARP32835_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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Hintergrund
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RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RIP3
Protein Interaction Partner: RIPK1,TICAM1,TNFRSF1A,TRAF2,RIPK1,TICAM1,TNFRSF1A,TRAF2
Protein Size: 518 -
Molekulargewicht
- 57 kDa
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Gen-ID
- 11035
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NCBI Accession
- NM_006871, NP_006862
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UniProt
- Q9Y572
Target
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