Ras Homolog Gene Family, Member B (RHOB) (Middle Region) Peptid
RHOB
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982961
Kurzübersicht für Ras Homolog Gene Family, Member B (RHOB) (Middle Region) Peptid (ABIN982961)
Target
RHOB
(Ras Homolog Gene Family, Member B (RHOB))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RHOB Antibody(ARP54702_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RHOB (Ras Homolog Gene Family, Member B (RHOB))
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Hintergrund
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RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Alias Symbols: ARH6, ARHB, MST081, MSTP081, RHOH6
Protein Interaction Partner: ARHGDIG,ARHGEF3,FNTA,PDE6D,PGGT1B,PPP2CA,RHPN2,ARHGDIG,ARHGEF3,CIT,PDE6D,RHPN2
Protein Size: 196 -
Molekulargewicht
- 22 kDa
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Gen-ID
- 388
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NCBI Accession
- NM_004040, NP_004031
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UniProt
- P62745
Target
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