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RE1-Silencing Transcription Factor (REST) (Middle Region) Peptid

REST Reaktivität: Maus Wirt: Synthetic BP, WB

Produktnummer ABIN982857

Kurzübersicht für RE1-Silencing Transcription Factor (REST) (Middle Region) Peptid (ABIN982857)

Target

REST (RE1-Silencing Transcription Factor (REST))

Spezies

Maus

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

Middle Region

Sequenz

ANMGMALTND MYDLHELSKA ELAAPQLIML ANVALTGEAS GSCCDYLVGE

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti-Rest Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Aufreinigung

Purified
RE1-Silencing Transcription Factor (REST) peptide
REST Wirt: Synthetic BP, Imm

RE1-Silencing Transcription Factor (REST) peptide
REST Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC

RE1-Silencing Transcription Factor (REST) (N-Term) peptide
REST Reaktivität: Human Wirt: Synthetic BP, WB

RE1-Silencing Transcription Factor (REST) (Middle Region) peptide
REST Reaktivität: Human Wirt: Synthetic BP, WB

RE1-Silencing Transcription Factor (REST) peptide
REST Reaktivität: Human, Maus, Ratte Wirt: Synthetic BP, WB, ICo, IDe

RE1-Silencing Transcription Factor (REST) peptide
REST Reaktivität: Human Wirt: Synthetic BP, BI

Applikationshinweise

Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Konzentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

REST (RE1-Silencing Transcription Factor (REST))

Hintergrund

Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Alias Symbols: 2610008J04Rik, AA407358, MGC150099, NRSF

Protein Size: 1082

Molekulargewicht

118 kDa

Gen-ID

19712

NCBI Accession

NM_011263, NP_035393

UniProt

Q8VIG1

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