RE1-Silencing Transcription Factor (REST) (Middle Region) Peptid
REST
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982856
Kurzübersicht für RE1-Silencing Transcription Factor (REST) (Middle Region) Peptid (ABIN982856)
Target
REST
(RE1-Silencing Transcription Factor (REST))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-REST antibody (Catalog #: ARP32478_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- REST (RE1-Silencing Transcription Factor (REST))
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Hintergrund
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REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described, however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NRSF, XBR
Protein Interaction Partner: CTDSP1,EHMT2,GRM2,STMN2,HTT,RCOR1,SIN3B,HDAC1,HDAC2,Hdac1,KDM5C,NCOR1,RCOR1,RNF2,Sin3a,Sin3b
Protein Size: 1097 -
Molekulargewicht
- 122 kDa
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Gen-ID
- 5978
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NCBI Accession
- NM_005612, NP_005603
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UniProt
- Q13127
Target
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