Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) (Middle Region) Peptid
RECK
Reaktivität: Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN982824
Kurzübersicht für Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) (Middle Region) Peptid (ABIN982824)
Target
RECK
(Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
Spezies
Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Reck Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Hintergrund
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Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971 -
Molekulargewicht
- 104 kDa
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Gen-ID
- 53614
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NCBI Accession
- NM_016678, NP_057887
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UniProt
- Q9Z0J1
Target
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