Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) (Middle Region) Peptid
RECK
Reaktivität: Maus
Wirt: Synthetic
BP, WB
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- Target Alle RECK Produkte
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Protein Region
- Middle Region
- Spezies
- Maus
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Reck Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Hintergrund
-
Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971 - Molekulargewicht
- 104 kDa
- Gen-ID
- 53614
- NCBI Accession
- NM_016678, NP_057887
- UniProt
- Q9Z0J1
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