Regulator of Calcineurin 1 (RCAN1) (N-Term) Peptid
RCAN1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982786
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Regulator of Calcineurin 1 (RCAN1) (N-Term) Peptid (ABIN982786)
Target
RCAN1
(Regulator of Calcineurin 1 (RCAN1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RCAN1 Antibody(ARP57857_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Hintergrund
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RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: GSK3B,MAP3K3,MAPK3,PPP3CA,UXT,PPP3CA,UBC
Protein Size: 252 -
Molekulargewicht
- 28 kDa
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Gen-ID
- 1827
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NCBI Accession
- NM_004414, NP_004405
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UniProt
- P53805
Target
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