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Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1) (Middle Region) Peptid

RASGRF1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982675
  • Target Alle RASGRF1 Produkte
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    PMSEKGKITR GRLGSLSLKK EGERQCFLFS KHLIICTRGS GGKLHLTKNG
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-RASGRF1 Antibody(ARP56515_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    Synonyme
    CDC25 Peptide, CDC25L Peptide, GNRP Peptide, GRF1 Peptide, GRF55 Peptide, H-GRF55 Peptide, PP13187 Peptide, ras-GRF1 Peptide, AI844718 Peptide, CDC25Mm Peptide, Grf1 Peptide, Grfbeta Peptide, P190-A Peptide, Ras-GRF1 Peptide, p190 Peptide, p190RhoGEF Peptide, cdc25 Peptide, rasgrf1 Peptide, Ras protein specific guanine nucleotide releasing factor 1 Peptide, RAS protein-specific guanine nucleotide-releasing factor 1 Peptide, Ras protein specific guanine nucleotide releasing factor 1 S homeolog Peptide, si:ch211-234p18.3 Peptide, RASGRF1 Peptide, Rasgrf1 Peptide, rasgrf1.S Peptide, si:ch211-234p18.3 Peptide, rasgrf1 Peptide
    Hintergrund
    The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Alias Symbols: CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1

    Protein Interaction Partner: NTRK1,NTRK2,NTRK3,PRKACA,RAC1,RHOA,RRAS2,TNK2,USP8,YWHAE,HRAS,MARK3,PPP1R9B,UBC,YWHAB

    Protein Size: 1273
    Molekulargewicht
    145 kDa
    Gen-ID
    5923
    NCBI Accession
    NM_002891, NP_002882
    UniProt
    Q13972
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