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RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (C-Term) Peptid

RASAL1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982671
  • Target Alle RASAL1 Produkte
    RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-RASAL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
    Hintergrund
    The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

    Alias Symbols: RASAL

    Protein Interaction Partner: PITX1

    Protein Size: 804
    Molekulargewicht
    88 kDa
    Gen-ID
    8437
    NCBI Accession
    NM_004658, NP_004649
    UniProt
    O95294
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