RAD9 Homolog A (S. Pombe) (RAD9A) Peptid
RAD9A
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für RAD9 Homolog A (S. Pombe) (RAD9A) Peptid (ABIN982618)
Target
RAD9A
(RAD9 Homolog A (S. Pombe) (RAD9A))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RAD9A antibody (Catalog #: AVARP03028_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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RAD9 Homolog A (S. Pombe) (RAD9A) peptide
RAD9A Reaktivität: Human, Hund, Maus Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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Hintergrund
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RAD9A is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM].
Alias Symbols: RAD9
Protein Interaction Partner: DNAJC7,HUS1,HUS1,RPA1,RPA2,ABL1,AR,ATAD5,ATM,BCL2,BCL2L1,CHEK2,CLSPN,DNAJC7,HDAC1,HUS1,HUS1B,ITSN2,MLH1,PCNA,RAD17,RAD9B,TOPBP1,ABL1,AR,BCL2,BCL2L1,CLSPN,DNAJC7,FEN1,HDAC1,HUS1,HUS1B,NR3C1,RAD1,RAD17,RPA1,RPA2,TOPBP1
Protein Size: 391 -
Molekulargewicht
- 42 kDa
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Gen-ID
- 5883
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NCBI Accession
- NM_004584, NP_004575
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UniProt
- Q99638
Target
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