Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptid
PYHIN1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982510
Kurzübersicht für Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptid (ABIN982510)
Target
PYHIN1
(Pyrin and HIN Domain Family, Member 1 (PYHIN1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalog #: ARP50875_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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Hintergrund
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PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Size: 492 -
Molekulargewicht
- 55 kDa
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Gen-ID
- 149628
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NCBI Accession
- NM_152501, NP_689714
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UniProt
- Q6K0P9
Target
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