This is a synthetic peptide designed for use in combination with anti- PURA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
PURA
(Purine-Rich Element Binding Protein A (PURA))
Synonyme
CAGER-1 Peptide, Pur-alpha Peptide, ssCRE-BP Peptide, PUR-ALPHA Peptide, PUR1 Peptide, PURALPHA Peptide, zgc:103411 Peptide, pur-alpha Peptide, pur1 Peptide, puralpha Peptide, purine-rich element binding protein A Peptide, purine rich element binding protein A Peptide, purine-rich element binding protein Aa Peptide, purine-rich element binding protein A L homeolog Peptide, pura Peptide, Pura Peptide, PURA Peptide, puraa Peptide, pura.L Peptide
Hintergrund
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.