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Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptid

PURA Reaktivität: Human Wirt: Synthetic BP, WB

Produktnummer ABIN982476

Kurzübersicht für Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptid (ABIN982476)

Target

PURA (Purine-Rich Element Binding Protein A (PURA))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Sequenz

MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA

Produktmerkmale

This is a synthetic peptide designed for use in combination with anti- PURA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Aufreinigung

Purified
Purine-Rich Element Binding Protein A (PURA) peptide
PURA Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC

Purine-Rich Element Binding Protein A (PURA) (N-Term) peptide
PURA Reaktivität: Human Wirt: Synthetic BP, WB

Purine-Rich Element Binding Protein A (PURA) (Middle Region) peptide
PURA Reaktivität: Human Wirt: Synthetic BP, WB, IHC

Purine-Rich Element Binding Protein A (PURA) (C-Term) peptide
PURA Reaktivität: Maus Wirt: Synthetic BP, WB

Applikationshinweise

Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Konzentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

PURA (Purine-Rich Element Binding Protein A (PURA))

Hintergrund

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Alias Symbols: PUR1, MRD31, PURALPHA, PUR-ALPHA

Protein Size: 322

Molekulargewicht

35 kDa

Gen-ID

5813

NCBI Accession

NM_005859, NP_005850

UniProt

Q00577

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