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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptid

PSMD8 Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN982388

Kurzübersicht für Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptid (ABIN982388)

Target

PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PSMD8 antibody (Catalog #: ARP48216_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

    Hintergrund

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

    Alias Symbols: HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31

    Protein Interaction Partner: UCHL5,SMAD2,SMAD9,UCHL5,PAAF1,PSMD13,PSMD6,UCHL5

    Protein Size: 257

    Molekulargewicht

    27 kDa

    Gen-ID

    5714

    UniProt

    P48556
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