Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) Peptid
PSENEN
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982323
Kurzübersicht für Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) Peptid (ABIN982323)
Target
PEN2 (PSENEN)
(Presenilin Enhancer 2 Homolog (PSENEN))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- SQIKGYVWRS AVGFLFWVIV LTSWITIFQI YRPRWGALGD YLSFTIPLGT
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PSENEN Antibody(ARP59439_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
-
Hintergrund
-
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Alias Symbols: MDS033, MSTP064, PEN-2, PEN2
Protein Interaction Partner: APH1A,NCSTN,PSEN1,APH1A,NCSTN,PSEN1,PSEN2,TMED10,APH1A,NCSTN,PSEN1,PSEN2
Protein Size: 101 -
Molekulargewicht
- 12 kDa
-
Gen-ID
- 55851
-
NCBI Accession
- NM_172341, NP_758844
-
UniProt
- Q9NZ42
Target
-
Sie sind hier:
