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Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3) (N-Term) Peptid

PRKAG3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982211
  • Target Alle PRKAG3 Produkte
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    ENSSSWPSPA VTSSSERIRG KRRAKALRWT RQKSVEEGEP PGQGEGPRSR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PRKAG3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    Hintergrund
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

    Alias Symbols: AMPKG3

    Protein Interaction Partner: PRKAA1,PRKAB1,PRKAB2

    Protein Size: 489
    Molekulargewicht
    54 kDa
    Gen-ID
    53632
    NCBI Accession
    NM_017431, NP_059127
    UniProt
    Q9UGI9
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