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PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) Peptid

PRDM1 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN982162
  • Target Alle PRDM1 Produkte
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PRDM1 antibody (Catalog #: P100596_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    Hintergrund
    PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

    Alias Symbols: BLIMP1, MGC118922, MGC118923, MGC118924, MGC118925, PRDI-BF1

    Protein Interaction Partner: AES,ATXN1,IRF4,TLE1,TLE2,EHMT2,HDAC1,HDAC2,HIST2H3A,KDM1A,PRMT5,PRMT7,SUV39H1,TLE1,TLE2

    Protein Size: 691
    Molekulargewicht
    77 kDa
    Gen-ID
    639
    NCBI Accession
    NM_182907, NP_878911
    UniProt
    Q86WM7
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