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PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) Peptid

PRDM1 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN982162

Kurzübersicht für PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) Peptid (ABIN982162)

Target

PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Spezies

Human

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein Region

    Middle Region

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PRDM1 antibody (Catalog #: P100596_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

    Hintergrund

    PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

    Alias Symbols: BLIMP1, MGC118922, MGC118923, MGC118924, MGC118925, PRDI-BF1

    Protein Interaction Partner: AES,ATXN1,IRF4,TLE1,TLE2,EHMT2,HDAC1,HDAC2,HIST2H3A,KDM1A,PRMT5,PRMT7,SUV39H1,TLE1,TLE2

    Protein Size: 691

    Molekulargewicht

    77 kDa

    Gen-ID

    639

    NCBI Accession

    NM_182907, NP_878911

    UniProt

    Q86WM7
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