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POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptid

POU3F3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982009

Kurzübersicht für POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptid (ABIN982009)

Target

POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-POU3F3 antibody (Catalog #: ARP33062_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

    Hintergrund

    POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].

    Alias Symbols: BRN1, OTF8

    Protein Interaction Partner: POU3F4,PPP1R15A,SOX10,SOX11,SOX8,POU3F4

    Protein Size: 500

    Molekulargewicht

    50 kDa

    Gen-ID

    5455

    NCBI Accession

    NM_006236, NP_006227

    UniProt

    P20264
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