Polynucleotide Kinase 3'-Phosphatase (PNKP) (N-Term) Peptid
PNKP
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981900
Kurzübersicht für Polynucleotide Kinase 3'-Phosphatase (PNKP) (N-Term) Peptid (ABIN981900)
Target
PNKP
(Polynucleotide Kinase 3'-Phosphatase (PNKP))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PNKP Antibody(ARP52311_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Hintergrund
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This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Alias Symbols: PNK, MCSZ, EIEE10
Protein Interaction Partner: XRCC1,KRTAP4-12,MAGEA11,MYOZ1,SMAD5,TRIM37,XRCC1,XRCC4,ATAD3B,DDX20,HEATR2,KRTAP4-12,LAS1L,LIG3,LIG4,MAGEA11,MCM3,MYOZ1,NOL3,NOM1,NUP93,POLB,SLC25A12,TRIM37,XRCC1,XRCC4,YWHAQ
Protein Size: 521 -
Molekulargewicht
- 57 kDa
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Gen-ID
- 11284
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NCBI Accession
- NM_007254, NP_009185
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UniProt
- Q96T60
Target
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