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Polynucleotide Kinase 3'-Phosphatase (PNKP) (N-Term) Peptid

PNKP Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981900
  • Target Alle PNKP Produkte
    PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PNKP Antibody(ARP52311_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
    Hintergrund
    This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

    Alias Symbols: PNK, MCSZ, EIEE10

    Protein Interaction Partner: XRCC1,KRTAP4-12,MAGEA11,MYOZ1,SMAD5,TRIM37,XRCC1,XRCC4,ATAD3B,DDX20,HEATR2,KRTAP4-12,LAS1L,LIG3,LIG4,MAGEA11,MCM3,MYOZ1,NOL3,NOM1,NUP93,POLB,SLC25A12,TRIM37,XRCC1,XRCC4,YWHAQ

    Protein Size: 521
    Molekulargewicht
    57 kDa
    Gen-ID
    11284
    NCBI Accession
    NM_007254, NP_009185
    UniProt
    Q96T60
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