Paired-Like Homeodomain 2 (PITX2) (N-Term) Peptid

Details zu Produkt Nr. ABIN981798, Anbieter: Anmelden zum Anzeigen
Proteinname
  • ARP1
  • Brx1
  • IDG2
  • IGDS
  • IGDS2
  • IHG2
  • IRID2
  • Otlx2
  • PTX2
  • RGS
  • RIEG
  • RIEG1
  • RS
  • 9430085M16Rik
  • Brx1a
  • Brx1b
  • Munc30
  • Pitx2a
  • Pitx2b
  • Pitx2c
  • Pitx2cbeta
  • Ptx2
  • Rieg
  • pitx2a
  • pitx2c
  • zgc:110508
  • XPtx2b
  • xPtx2
  • xpitx2
  • arp1
  • brx1
  • idg2
  • igds
  • igds2
  • ihg2
  • irid2
  • otlx2
  • pitx2-A
  • ptx2
  • rgs
  • rieg
  • rieg1
  • pitx-2
  • pitx2
  • paired like homeodomain 2
  • paired-like homeodomain transcription factor 2
  • paired-like homeodomain 2
  • paired like homeodomain 2 S homeolog
  • paired like homeodomain 2 L homeolog
  • PITX2
  • Pitx2
  • pitx2
  • pitx2.S
  • pitx2.L
Protein Region
N-Term
Spezies
Human
3
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Geblockter Antikörper anti-PITX2 Antikörper (Paired-Like Homeodomain 2) (N-Term) (ABIN2779638)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PITX2 antibody (Catalog #: ARP32432_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alias Symbols: ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, MGC111022, MGC20144, Otlx2, PTX2, RGS, RIEG, RIEG1, RS

Protein Interaction Partner: CTNNB1,HDAC1,KAT5,LEF1,PDLIM1,PITX2,PROP1,HERC5,MSX2,PITX2,Pou1f1,TRIM25

Protein Size: 317
Molekulargewicht 35 kDa
Gen-ID 5308
NCBI Accession NM_153426, NP_700475
UniProt Q99697
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.