PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptid
PINX1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981775
Kurzübersicht für PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptid (ABIN981775)
Target
PINX1
(PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PINX1 Antibody(ARP57058_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) peptide
PINX1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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Hintergrund
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PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Alias Symbols: FLJ20565, LPTL, LPTS, MGC8850
Protein Interaction Partner: MCRS1,MPZ,PAFAH1B2,TERF1,TERT,AHCY,CALM3,CAPRIN1,GTPBP4,HRNR,MCRS1,PABPC1,PABPC4,PAFAH1B2,PLEKHJ1,RPL23A,RPL31,RPS10,RPS16,RPS19,RPS28,RPS3A,TERF1,TERT,TXN
Protein Size: 328 -
Molekulargewicht
- 37 kDa
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Gen-ID
- 54984
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NCBI Accession
- NM_017884, NP_060354
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UniProt
- Q96BK5
Target
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