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Peptidase Inhibitor 3, Skin-Derived (PI3) (N-Term) Peptid

PI3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981719

Kurzübersicht für Peptidase Inhibitor 3, Skin-Derived (PI3) (N-Term) Peptid (ABIN981719)

Target

PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PI3 antibody (Catalog #: ARP45340_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

    Hintergrund

    PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin

    Protein Interaction Partner: CELA1,EVPL,CSTA,KRT1,LOR

    Protein Size: 117

    Molekulargewicht

    6 kDa

    Gen-ID

    5266

    NCBI Accession

    NM_002638, NP_002629

    UniProt

    P19957
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