6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) Peptid
PFKFB1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981614
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 21 Werktagen
Kurzübersicht für 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) (C-Term) Peptid (ABIN981614)
Target
PFKFB1
(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- EEMTYEEIQE HYPEEFALRD QDKYRYRYPK GESYEDLVQR LEPVIMELER
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PFKFB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
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Hintergrund
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This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Alias Symbols: F6PK, HL2K, MGC116715, MGC116717, PFRX
Protein Size: 471 -
Molekulargewicht
- 52 kDa
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Gen-ID
- 5207
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NCBI Accession
- NM_002625, NP_002616
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UniProt
- P16118
Target
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