Peroxisomal Biogenesis Factor 5 (PEX5) (N-Term) Peptid

Details zu Produkt Nr. ABIN981604, Anbieter: Anmelden zum Anzeigen
Proteinname
  • AW212715
  • ESTM1
  • PTS1R
  • Pxr1
  • X83306
  • PTS1-BP
  • PBD2A
  • PBD2B
  • PXR1
  • Peroxin-5
  • peroxisomal biogenesis factor 5
  • pex5
  • Pex5
  • PEX5
Protein Region
N-Term
Spezies
Human
2
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-PEX5 Antikörper (Peroxisomal Biogenesis Factor 5) (N-Term) (ABIN2786512)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-PEX5 antibody (Catalog #: ARP56101_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Proteinname Peroxisomal Biogenesis Factor 5 (PEX5)
Hintergrund PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD).

Alias Symbols: PTS1R, PXR1, PTS1-BP

Protein Interaction Partner: PEX12,PEX14,AGXT,ATM,DDO,HSPA1A,PDZK1,PEX10,PEX12,PEX13,PEX14,PEX7,SCARB1,SIRT3,SNUPN,SSTR5,ATM,CAT,DDO,PDZK1,PEX10,PEX12,PEX13,PEX14,PEX7,SIRT3,SNUPN

Protein Size: 631
Molekulargewicht 70 kDa
Gen-ID 5830
NCBI Accession NM_000319, NP_000310
Applikations-hinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.