Paternally Expressed 3 (PEG3) Peptid
PEG3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Paternally Expressed 3 (PEG3) Peptid (ABIN981577)
Target
PEG3
(Paternally Expressed 3 (PEG3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PEG3 antibody (Catalog #: ARP38756_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEG3 (Paternally Expressed 3 (PEG3))
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Hintergrund
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PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: SIAH1,SIAH2,TRAF2,USP7,BRCA1,SIAH1,SIAH2
Protein Size: 1588 -
Molekulargewicht
- 181 kDa
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Gen-ID
- 5178
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NCBI Accession
- NM_006210, NP_006201
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UniProt
- Q9GZU2
Target
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