phosphodiesterase 4B, cAMP-Specific (PDE4B) (Middle Region) Peptid
PDE4B
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für phosphodiesterase 4B, cAMP-Specific (PDE4B) (Middle Region) Peptid (ABIN981510)
Target
PDE4B
(phosphodiesterase 4B, cAMP-Specific (PDE4B))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PDE4B antibody (Catalog #: ARP56256_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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phosphodiesterase 4B, cAMP-Specific (PDE4B) peptide
PDE4B Reaktivität: Human, Maus, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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Hintergrund
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The specific function of this protein remains unknown.This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DKFZp686F2182, DPDE4, MGC126529, PDE4B5, PDEIVB
Protein Interaction Partner: PRKACA
Protein Size: 564 -
Molekulargewicht
- 64 kDa
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Gen-ID
- 5142
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NCBI Accession
- NM_001037339, NP_001032416
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UniProt
- Q5TEK5
Target
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