phosphodiesterase 11A (PDE11A) (N-Term) Peptid
PDE11A
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981500
Kurzübersicht für phosphodiesterase 11A (PDE11A) (N-Term) Peptid (ABIN981500)
Target
PDE11A
(phosphodiesterase 11A (PDE11A))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- RRASQKELRK SFARSKAIHV NRTYDEQVTS RAQEPLSSVR RRALLRKASS
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE11A (phosphodiesterase 11A (PDE11A))
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Hintergrund
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The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ23693, MGC133355, MGC133356, PPNAD2
Protein Size: 933 -
Molekulargewicht
- 105 kDa
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Gen-ID
- 50940
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NCBI Accession
- NM_016953, NP_058649
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UniProt
- Q9HCR9
Target
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