Protocadherin alpha 12 (PCDHA12) (N-Term) Peptid
PCDHA12
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle PCDHA12 Produkte
- PCDHA12 (Protocadherin alpha 12 (PCDHA12))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PCDHA12 antibody (Catalog #: ARP49348_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PCDHA12 (Protocadherin alpha 12 (PCDHA12))
- Synonyme
- PCDH-ALPHA12 Peptide, Pcdha11 Peptide, rCNRv12 Peptide, Cnr5 Peptide, Crnr5 Peptide, Pcdha13 Peptide, CNRv12 Peptide, PCDHA12 Peptide, protocadherin alpha 12 Peptide, protocadherin alpha-12 Peptide, PCDHA12 Peptide, Pcdha12 Peptide, LOC102147933 Peptide
- Hintergrund
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PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: MGC138485, MGC141932, PCDH-ALPHA12
Protein Size: 941 - Molekulargewicht
- 99 kDa
- Gen-ID
- 56137
- NCBI Accession
- NM_018903, NP_061726
- UniProt
- Q9UN75
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