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Protocadherin-15 (PCDH15) Peptid

PCDH15 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981439

Kurzübersicht für Protocadherin-15 (PCDH15) Peptid (ABIN981439)

Target

PCDH15 (Protocadherin-15 (PCDH15))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PCDH15 antibody (Catalog #: ARP50153_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PCDH15 (Protocadherin-15 (PCDH15))

    Hintergrund

    PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

    Alias Symbols: RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15

    Protein Size: 719

    Molekulargewicht

    80 kDa

    Gen-ID

    65217

    NCBI Accession

    NM_001142763

    UniProt

    A2A3E5
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