Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptid
Kurzübersicht für Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptid (ABIN981324)
Target
Spezies
Quelle
Applikation
-
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PAM antibody (Catalog #: ARP43512_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
-
Hintergrund
-
PAM is a multifunctional protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Alias Symbols: PAL, PHM
Protein Interaction Partner: KALRN,PRKCA,RASSF9,TSC2,UHMK1,KALRN,RASSF9,TSC1,TSC2
Protein Size: 974 -
Molekulargewicht
- 108 kDa
-
Gen-ID
- 5066
-
NCBI Accession
- NM_000919, NP_000910
-
UniProt
- A6NMR0
Target
-