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Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptid

PAM Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981324

Kurzübersicht für Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptid (ABIN981324)

Target

PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PAM antibody (Catalog #: ARP43512_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

    Hintergrund

    PAM is a multifunctional protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.

    Alias Symbols: PAL, PHM

    Protein Interaction Partner: KALRN,PRKCA,RASSF9,TSC2,UHMK1,KALRN,RASSF9,TSC1,TSC2

    Protein Size: 974

    Molekulargewicht

    108 kDa

    Gen-ID

    5066

    NCBI Accession

    NM_000919, NP_000910

    UniProt

    A6NMR0
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