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Proliferation-Associated 2G4, 38kDa (PA2G4) (C-Term) Peptid

PA2G4 Reaktivität: Maus Wirt: Synthetic BP, WB
Produktnummer ABIN981293
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Proliferation-Associated 2G4, 38kDa (PA2G4) (C-Term) Peptid (ABIN981293)

Target

PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Spezies

Maus

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    PDLYKSEMEV QDAELKALLQ SSASRKTQKK KKKKASKTVE NATSGETLEE

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-Pa2g4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

    Hintergrund

    Pa2g4 may play a role in a ERBB3-regulated signal transduction pathway. It seems be involved in growth regulation. It acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). It inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. It may be involved in ribosome assembly. It mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). It together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES.

    Alias Symbols: 38 kDa, AA672939, Ebp1, Plfap

    Protein Size: 394

    Molekulargewicht

    44 kDa

    Gen-ID

    18813

    NCBI Accession

    NM_011119, NP_035249

    UniProt

    P50580
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