Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) Peptid
P4HB
Reaktivität: Human
Wirt: Synthetic
BP, IHC, WB
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- Target Alle P4HB Produkte
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-P4HB antibody (Catalog #: ARP48150_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
- Synonyme
- DSI Peptide, ERBA2L Peptide, GIT Peptide, P4Hbeta Peptide, PDI Peptide, PDIA1 Peptide, PHDB Peptide, PO4DB Peptide, PO4HB Peptide, PROHB Peptide, PDA2 Peptide, PDIP Peptide, PDIR Peptide, ERp59 Peptide, Pdia1 Peptide, Thbp Peptide, p55 Peptide, XPDIp Peptide, pdi Peptide, 1810041F13Rik Peptide, AI661267 Peptide, Pdip Peptide, Pdipl Peptide, p58 Peptide, prolyl 4-hydroxylase subunit beta Peptide, protein disulfide isomerase family A member 2 Peptide, prolyl 4-hydroxylase, beta polypeptide Peptide, protein disulfide isomerase family A member 2 L homeolog Peptide, protein disulfide isomerase associated 2 Peptide, prolyl 4-hydroxylase subunit beta L homeolog Peptide, protein disulfide-isomerase Peptide, P4HB Peptide, PDIA2 Peptide, P4hb Peptide, pdia2.L Peptide, Pdia2 Peptide, p4hb.L Peptide, LOC8281065 Peptide
- Hintergrund
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P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DSI, ERBA2L, GIT, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, P4Hbeta
Protein Interaction Partner: CD1D,COL10A1,COL1A1,COL1A2,EIF2S1,ERO1L,ERO1LB,FEZ1,P4HA2,P4HA3,P4HB,PRNP,PTN,TG,UBQLN1,YWHAG,CD2BP2,CUL2,EIF4A2,ELF3,ERO1L,ERO1LB,FEZ1,P4ha2,PTN,PUF60,TG,TNFRSF14,TRIP6,UBQLN1
Protein Size: 508 - Molekulargewicht
- 55 kDa
- Gen-ID
- 5034
- NCBI Accession
- NM_000918, NP_000909
- UniProt
- P07237
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