Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptid
P4HA1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981287
Kurzübersicht für Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) (Middle Region) Peptid (ABIN981287)
Target
P4HA1
(Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- MAKEKDVNKS ASDDQSDQKT TPKKKGVAVD YLPERQKYEM LCRGEGIKMT
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-P4HA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P4HA1 (Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
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Hintergrund
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This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: P4HA
Protein Size: 516 -
Molekulargewicht
- 56 kDa
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Gen-ID
- 5033
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NCBI Accession
- NM_001142596, NP_001136068
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UniProt
- C9JL12
Target
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