This is a synthetic peptide designed for use in combination with anti-ONECUT1 antibody (Catalog #: ARP38480_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
ONECUT1
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
ONECUT1
(One Cut Homeobox 1 (ONECUT1))
Hintergrund
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Alias Symbols: HNF-6, HNF6, HNF6A
Protein Interaction Partner: CREBBP,FOXA2,KAT2B,NR3C1,CREBBP,FOXA1,FOXA2,KAT2B,NR3C1