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Ornithine Decarboxylase Antizyme 3 (OAZ3) (Middle Region) Peptid

OAZ3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981081

Kurzübersicht für Ornithine Decarboxylase Antizyme 3 (OAZ3) (Middle Region) Peptid (ABIN981081)

Target

OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    DRRLFLDIPY QALDQGNRES LTATLEYVEE KTNVDSVFVN FQNDRNDRGA

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-OAZ3 Antibody(ARP53713_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

    Hintergrund

    Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: AZ3, OAZ-t, TISP15

    Protein Interaction Partner: GGN,OAZ1,SMAD1

    Protein Size: 187

    Molekulargewicht

    21 kDa

    Gen-ID

    51686

    NCBI Accession

    NM_016178, NP_057262

    UniProt

    Q9UMX2
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