2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) Peptid
OAS2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981074
Kurzübersicht für 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) Peptid (ABIN981074)
Target
OAS2
(2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-OAS2 antibody (Catalog #: ARP40852_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
-
Hintergrund
-
OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: MGC78578
Protein Size: 719 -
Molekulargewicht
- 82 kDa
-
Gen-ID
- 4939
-
NCBI Accession
- NM_016817, NP_058197
-
UniProt
- P29728
Target
-
Sie sind hier:
