Nuclear Mitotic Apparatus Protein 1 (NUMA1) Peptid
NUMA1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle NUMA1 Produkte
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NUMA1 antibody (Catalog #: ARP50532_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- Synonyme
- NUMA Peptide, 6720401E04Rik Peptide, AA764025 Peptide, AL022610 Peptide, AU014979 Peptide, NUMA1 Peptide, NuMA Peptide, SP-H Peptide, numa Peptide, numa1 Peptide, nuclear mitotic apparatus protein 1 Peptide, nuclear mitotic apparatus protein 1 S homeolog Peptide, NUMA1 Peptide, Numa1 Peptide, numa1 Peptide, numa1.S Peptide
- Hintergrund
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NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles.
Alias Symbols: NUMA
Protein Interaction Partner: GNAI1,GPSM2,ACTR1A,EPB41,EPB41L1,EPB41L2,GNAI1,GPSM2,NCOA6,PIM1,RAD21,SMC1A,TNKS,YEATS4,ACTR1A,EPB41,EPB41L1,EPB41L2,GPSM2,NCOA6,NPM1,PIM1,RPAP1,SMC1A,SMC3,TNKS,YEATS4
Protein Size: 2115 - Molekulargewicht
- 238 kDa
- Gen-ID
- 4926
- NCBI Accession
- NM_006185, NP_006176
- UniProt
- Q14980
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