NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (C-Term) Peptid
NQO1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN980860
Kurzübersicht für NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (C-Term) Peptid (ABIN980860)
Target
NQO1
(NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NQO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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NAD(P)H Dehydrogenase, Quinone 1 (NQO1) peptide
NQO1 Reaktivität: Human, Hund, Maus, Schwein, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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Hintergrund
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Protein Interaction Partner: DNAJB1,HSPA1A,NQO1,TP53,HSPA4,ING1,NQO1
Protein Size: 274 -
Molekulargewicht
- 31 kDa
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Gen-ID
- 1728
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NCBI Accession
- NM_000903, NP_000894
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UniProt
- P15559
Target
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