Neuronal Pentraxin II (NPTX2) (N-Term) Peptid
NPTX2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN980857
Kurzübersicht für Neuronal Pentraxin II (NPTX2) (N-Term) Peptid (ABIN980857)
Target
NPTX2
(Neuronal Pentraxin II (NPTX2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- VQQKETLGAQ REAIRELTGK LARCEGLAGG KARGAGATGK DTMGDLPRDP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NPTX2 Antibody(ARP56365_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NPTX2 (Neuronal Pentraxin II (NPTX2))
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Hintergrund
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This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NARP, NP-II, NP2
Protein Interaction Partner: NPTXR,Nptx1,Nptxr
Protein Size: 431 -
Molekulargewicht
- 47 kDa
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Gen-ID
- 4885
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NCBI Accession
- NM_002523, NP_002514
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UniProt
- P47972
Target
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