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NK2 Homeobox 5 (NKX2-5) (N-Term) Peptid

NKX2-5 Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN980742
  • Target Alle NK2 Homeobox 5 (NKX2-5) Produkte
    NK2 Homeobox 5 (NKX2-5)
    Protein Region
    N-Term
    Spezies
    Human, Maus
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-Nkx2-5 antibody (Catalog #: ARP36946_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NK2 Homeobox 5 (NKX2-5)
    Synonyme
    CHNG5 Peptide, CSX Peptide, CSX1 Peptide, HLHS2 Peptide, NKX2.5 Peptide, NKX2E Peptide, NKX4-1 Peptide, VSD3 Peptide, Csx Peptide, Nkx-2.5 Peptide, Nkx2.5 Peptide, tinman Peptide, nk2.5 Peptide, nkx2-5 Peptide, zgc:111912 Peptide, AR2 Peptide, XNkx2-5 Peptide, csx Peptide, nkx-2.5 Peptide, nkx2-5b Peptide, nkx2.5 Peptide, NKX2-5 Peptide, Nkx2-5 Peptide, csx1 Peptide, nkx2e Peptide, XNkx-2.5 Peptide, CNKX-2.5 Peptide, NKX-2.5 Peptide, NK2 homeobox 5 Peptide, NK2 homeobox 5 S homeolog Peptide, NKX2-5 Peptide, Nkx2-5 Peptide, nkx2.5 Peptide, nkx2-5.S Peptide, nkx2-5 Peptide
    Hintergrund
    Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.

    Alias Symbols: Csx, Nkx-2.5, Nkx2.5, tinman

    Protein Interaction Partner: Foxh1,Mef2c,Smarca4,SRF,SRF

    Protein Size: 318
    Molekulargewicht
    34 kDa
    Gen-ID
    18091
    NCBI Accession
    NM_008700, NP_032726
    UniProt
    P42582
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