NK2 Homeobox 5 (NKX2-5) (N-Term) Peptid
NKX2-5
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN980742
Kurzübersicht für NK2 Homeobox 5 (NKX2-5) (N-Term) Peptid (ABIN980742)
Target
NK2 Homeobox 5 (NKX2-5)
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Nkx2-5 antibody (Catalog #: ARP36946_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NK2 Homeobox 5 (NKX2-5)
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Hintergrund
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Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.
Alias Symbols: Csx, Nkx-2.5, Nkx2.5, tinman
Protein Interaction Partner: Foxh1,Mef2c,Smarca4,SRF,SRF
Protein Size: 318 -
Molekulargewicht
- 34 kDa
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Gen-ID
- 18091
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NCBI Accession
- NM_008700, NP_032726
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UniProt
- P42582
Target
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