Nuclear Transcription Factor Y, gamma (NFYC) Peptid
NFYC
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN980693
Kurzübersicht für Nuclear Transcription Factor Y, gamma (NFYC) Peptid (ABIN980693)
Target
NFYC
(Nuclear Transcription Factor Y, gamma (NFYC))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NFYC antibody (Catalog #: ARP39066_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NFYC (Nuclear Transcription Factor Y, gamma (NFYC))
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Hintergrund
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NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.
Alias Symbols: CBF-C, CBFC, DKFZp667G242, FLJ45775, H1TF2A, HAP5, HSM, NF-YC
Protein Interaction Partner: MYC,ATF6,ATF6B,MYC,NFYA,NFYB,SMAD2,SMAD3,ATF6,ATF6B,MYC,SMAD2,SMAD3,TBP,TP73
Protein Size: 335 -
Molekulargewicht
- 37 kDa
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Gen-ID
- 4802
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NCBI Accession
- NM_014223, NP_055038
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UniProt
- Q13952
Target
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