Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Peptid
NFE2L2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN980656
Kurzübersicht für Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Peptid (ABIN980656)
Target
NRF2 (NFE2L2)
(Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NFE2L2 antibody (Catalog #: ARP38745_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Hintergrund
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NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM].
Alias Symbols: NRF2
Protein Interaction Partner: ATF4,CASP1,CASP3,CHD6,COPS7A,CREBBP,EIF2AK3,JUN,JUND,KEAP1,MAFF,MAFG,MAFK,NFE2,PMF1,PPARG,PRKCD,CREBBP,EIF2AK3,JUN,KEAP1,Keap1,MAFF,MAFK,PMF1,PPARG,UBC
Protein Size: 605 -
Molekulargewicht
- 68 kDa
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Gen-ID
- 4780
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NCBI Accession
- NM_006164, NP_006155
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UniProt
- Q16236
Target
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