Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Produktmerkmale
This is a synthetic peptide designed for use in combination with anti-NCOR1 antibody (Catalog #: ARP32479_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
NCOR1
(Nuclear Receptor Co-Repressor 1 (NCOR1))
Hintergrund
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
Alias Symbols: N-CoR, TRAC1, N-CoR1, hN-CoR
Protein Interaction Partner: CCL3,CCND2,CD82,CDKN2A,ERBB2,ESR1,ETS1,ETS2,GPS2,HDAC3,HTT,RARA,RUNX1T1,SIRT1,TBL1X,TBL1XR1,ACTN2,AR,ATXN1,BCL6,C1D,CBFA2T2,CHD1,DACH1,DDX20,DHX30,ESR1,ESR2,ETS1,ETS2,GPS2,HDAC3,HDAC5,HDAC9,HESX1,HEY2,HTT,MECP2,MYBL2,NCOR1,NR1D1,NR1D2,NR1H2,NR1H3,NR2E3,NR3C1,NR6A1,PDCD2,PHB,PML,PPARA,PPARD,PPARG,PTMA,RARA,RBPJ,RDBP,RUNX1T1,SAP30,SKI,SKIL,SP1,SPEN,TBL1X,TBL1XR1,THRA,THRB,TXNRD2,ZBTB16,ZBTB33,ZMYND11,AR,BCL6,CBFA2T3,CHD1,CLK1,CORO2A,DZIP3,ESR1,GPS2,HDAC3,HDAC4,HDAC5,HDAC7,HDAC9,HEY2,HSPA4,HTT,KDM4A,KDM5C,KIF11,MECP2,MYOD1,NCOA1,NCOR2,NFKB1,NR1D1,NR1D2,NR3C1,PDCD2,PHB,PML,PPARA,PPARD,PTMA,RARA,RARG,RDBP,REST,RUNX1T1,SAP30,SF3A1,SF3B3,SIN3A,SKI,SMARCA4,SMARCB1,SMARCC1,SMARCC2,SRCAP,TAB2,TBL1X,TBL1XR1,THRA,TRIM28,TRIM33,TXNRD2,VDR,ZBTB16,ZBTB33,ZMYND11