MUS81 Endonuclease Homolog (MUS81) (Middle Region) Peptid
MUS81
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN980383
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für MUS81 Endonuclease Homolog (MUS81) (Middle Region) Peptid (ABIN980383)
Target
MUS81
(MUS81 Endonuclease Homolog (MUS81))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- PEGLELAQKL AESEGLSLLN VGIGPKEPPG EETAVPGAAS AELASEAGVQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MUS81 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MUS81 (MUS81 Endonuclease Homolog (MUS81))
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Hintergrund
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MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Alias Symbols: FLJ21012, FLJ44872, SLX3
Protein Interaction Partner: CHEK2,EME1,MUS81,CHEK2,EME1,SLX1B,SLX4,SUMO2,TERF2,TERT
Protein Size: 551 -
Molekulargewicht
- 61 kDa
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Gen-ID
- 80198
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NCBI Accession
- NM_025128, NP_079404
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UniProt
- Q96NY9
Target
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