5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (N-Term) Peptid
MTRR
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN980362
Kurzübersicht für 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (N-Term) Peptid (ABIN980362)
Target
MTRR
(5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- YDLKTETAPL VVVVSTTGTG DPPDTARKFV KEIQNQTLPV DFFAHLRYGL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MTRR Antibody(ARP57657_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
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Hintergrund
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Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: MGC129643, MSR, cblE
Protein Interaction Partner: MMAB
Protein Size: 725 -
Molekulargewicht
- 80 kDa
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Gen-ID
- 4552
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NCBI Accession
- NM_024010, NP_076915
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UniProt
- Q9UBK8
Target
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