Metastasis Associated 1 (MTA1) Peptid
MTA1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN980315
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Metastasis Associated 1 (MTA1) Peptid (ABIN980315)
Target
MTA1
(Metastasis Associated 1 (MTA1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MTA1 antibody (Catalog #: ARP37737_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Metastasis Associated 1 (MTA1) peptide
MTA1 Reaktivität: Human Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTA1 (Metastasis Associated 1 (MTA1))
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Hintergrund
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MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
Protein Interaction Partner: BLOC1S1,ITGB3BP,MNAT1,BLOC1S1,CCNH,DDX18,DYNLL1,ESR1,GPR183,GRB2,HDAC1,HDAC2,HIF1A,ITGB3BP,MNAT1,RBBP4,SH3GLB1,TH1L,TP53,ATR,CCNH,CDK7,CHD4,ESR1,FOXP1,GPR183,HDAC1,HDAC2,HIF1A,MBD3L1,MNAT1,MTA1,MTA2,NAA10,RBBP4,RBBP7,SIN3A,TH1L,TP53
Protein Size: 430 -
Molekulargewicht
- 47 kDa
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Gen-ID
- 9112
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NCBI Accession
- NM_001203258
Target
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