This is a synthetic peptide designed for use in combination with anti-MLLT3 antibody (Catalog #: ARP38489_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
AF9 (MLLT3)
(Protein AF-9 (MLLT3))
Hintergrund
MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9,11)(p22,q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
Alias Symbols: AF9, FLJ2035, YEATS3
Protein Interaction Partner: AFF1,APPBP2,BCOR,C1orf103,C7orf64,CBX8,EEF1A1,MCM6,MLLT3,PTN,APPBP2,BCOR,C1orf103,C7orf64,DOT1L,EEF1A1,MCM6,PTN,SGK1