Mediator of Cell Motility 1 (MEMO1) (C-Term) Peptid
MEMO1
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, WB
Produktnummer ABIN979986
Kurzübersicht für Mediator of Cell Motility 1 (MEMO1) (C-Term) Peptid (ABIN979986)
Target
MEMO1
(Mediator of Cell Motility 1 (MEMO1))
Spezies
Human, Ratte
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- KLFSKYLADP SNLFVVSSDF CHWGQRFRYS YYDESQGEIY RSIEHLDKMG
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Memo1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- MEMO1 (Mediator of Cell Motility 1 (MEMO1))
-
Hintergrund
-
Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Memo1 is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Alias Symbols: MGC116222, RGD1309929
Protein Size: 297 -
Molekulargewicht
- 32 kDa
-
Gen-ID
- 298787
-
NCBI Accession
- NM_001029917, NP_001025088
-
UniProt
- Q4QQR9
Target
-
Sie sind hier:
